Acetyl-l-carnitine prevents and reduces paclitaxel-induced painful peripheral neuropathy
نویسندگان
چکیده
منابع مشابه
Acetyl-L-carnitine prevents and reduces paclitaxel-induced painful peripheral neuropathy.
This study examines the potential efficacy of acetyl-L-carnitine (ALC) to prevent and treat paclitaxel-induced pain. Rats received four intraperitoneal (i.p.) injections of 2 mg/kg paclitaxel on alternate days which, following a short delay induced marked mechanical hypersensitivity. Daily administration of ALC (50 mg/kg and 100 mg/kg; p.o.; concurrently with paclitaxel and for 14 days afterwar...
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ژورنال
عنوان ژورنال: Neuroscience Letters
سال: 2006
ISSN: 0304-3940
DOI: 10.1016/j.neulet.2005.12.013